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For patients with liver, kidney, hypertension, traumatic brain injuries, a tendency to epilepsy or drug addiction, the doctor selects the dose of the drug individually and monitors the patient’s condition during treatment. During therapy, alcohol intake should be excluded, since ethanol increases the depressing effect of the drug on the central nervous system. tramadol help migraines It has a strong and direct impact upon the cerebrum, blocking special nerve centers that are responsible for feeling of pain. Afterwards, all the tension in muscles would be gone and you will move freely again.